Story
Great idea for a josei. The heroine's body is saturated with poison, preventing her from ever being with anyone she loves. Her mission is to kill the king of an enemy country, but he seems to be a decent ruler and his handsome sons further complicate the plot. It has horror elements, including her best friend being burned alive and the suffering she went through eating poison as a child.

Art
Beautiful art. The costumes are elaborate and the character designs are all distinctive. For once it's easy to tell all the characters apart.

Character
The heroine is compassionate and conflicted. She was the "crybaby" back home but is resolved to fulfill her mission and survive. Not enough of the manga is out yet to comment on the other characters.

Enjoyment
Dark, but very enjoyable. Great for anyone who wants a slightly more mature story.

Overall
This is a really great idea for a manga. I'm excited to see where the author takes it.