tl;dr: Arbitrary nonsense. 

This manga felt incredibly terribly written. The two characters that were probably meant to be the most important, Ryoichi and Munakata, are an inconsistent mess, and as such their relationship which I suppose was meant to be the core of the manga, is similarly incredibly arbitrary and doesn’t really feel like it has any worth at all. I use the words “probably” and “suppose” because this manga is so random that I’m not entirely sure they are meant to be the focus as it's not like they really got the proper focus main characters should, but considering everything else matters even less I suppose they fit the bill. They’re not very likable though, in that Munakata is just kind of terrible all the way through, like a yandere that completely misses the point, and Ryoichi doesn’t do much of anything at all for the whole manga basically just being swept along by things. The two best characters were probably Kazumi, who was interesting in that he seemed crazy and never explained things but had it together and actually drove the plot forward, and Chiken who was totally out of her depth but tried her best in a traditional love interest type fashion. That isn’t enough to make them good characters though as considering the narrative it is really hard for any character to be all that good. The themes and tone were also all over the place, with random global warming connections and linking important concepts to Japanese mythology for no reason despite them being explained earlier or later as being due to DNA modification. It just felt like a long string of arbitrary twists leading up to an ending I still somehow managed to find disappointing. Also, the manga is about a lot of different things with it going in random directions completely randomly, but it's never about what the description of this manga describes it as, at least as of posting this, which is just frankly wrong. The art was okay for the most part, but the attempts at horror were terrible.