I've liked this manga a whole lot- especially the art and the psychology of the characters. Many people would criticize this manga for the complicated, psychological story, and also the way it continuously jumps from the present time to the past. In my case, I'm fascinated by how complexe the characters are- meaningful dialogues, where you have to read between the lines to realize what it really means that they're trying to say, the cruel realities that are confronted, and a little bit of over-dramatizing.

For people who don't like guro/gore, then I suggest you don't read it, because you won't like it. It's not a scary story per-se, and although it's a work of fiction, it's not exactly a sci-fi story. A lot of anatomy- if you're sensitive with death aspects and corpses, STAY AWAY. I mean it. It can get a bit too much and a sensitive stomach may have problems with it. But if you're tolerant of gore, then by all means try it. There is a whole alternate universe here, one that could be viewed as a variant of future, even. The conflict between morals, ethics and how imoral the world actually is makes the main character grow with every chapter. The realization drives him to take some extreme decisions, and certain convictions of his really match the phrase "the end justifies the means"

Du Ming can be easily viewed as an anti-hero/anti-villain, with harsh decisions that actually do some good despite how wrong the means are. The drop of insanity each character possesses makes Du Ming seem 'pure' at the beginning but as the series goes on, we discover that he is no exception to the inconsistencies of the world. Immorality, murder, deceit, sex, Du Ming goes through them all, maintaining a borderline sanity that every once in a while goes overboard. As a doctor, he is somewhat insensitive, but in fact his personality can be layered like an onion- read to know more.

As a conclusion, it's one of the best mangas I've read, and I'm sorry that so many people find it hard to cope with the fast-moving action and changing panels between present and past. Tip: try to figure out what each line means. The dialogues aren't there just to fill the space. They mean more than they seem. If you have patience you'll see the real psychology behind the apparently gore and strange story. Good luck!